SIRT6 anticorps (C-Term)

N° du produit ABIN783616

Cet anticorps Poulet Polyclonal détecte spécifiquement SIRT6 dans WB et EIA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour SIRT6 anticorps (C-Term) (ABIN783616)

Antigène: SIRT6 (Sirtuin 6 (SIRT6))

Reactivité: Humain, Souris, Rat

Hôte: Poulet

Clonalité: Polyclonal

Conjugué: Cet anticorp SIRT6 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-SIRT6 anticorps

Épitope: C-Term

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogène: 17 amino acid peptide near the carboxy terminus of human SIRT6

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur SIRT6

Antigène: SIRT6 (Sirtuin 6 (SIRT6))

Autre désignation: SIRT6

Sujet: The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT6 is a histone H3 lysine 9 deacetylase and is thought to stabilize the DNA-dependent protein kinase at double-stranded DNA breaks and may have a role in the process of mammalian aging.Synonyms: NAD-dependent deacetylase sirtuin-6, SIR2-like protein 6, SIR2L6, SIRT-6, sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae), sirtuin 6, sirtuin type 6, sirtuin-6

ID gène: 51548

NCBI Accession: NP_001180214

UniProt: Q8N6T7