SIRT3 anticorps (Center)

N° du produit ABIN783622

Détail du produit anti-SIRT3 anticorps

Antigène: SIRT3 (Sirtuin 3 (SIRT3))

Épitope: Center

Reactivité: Humain, Souris, Rat

Hôte: Poulet

Clonalité: Polyclonal

Conjugué: Cet anticorp SIRT3 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogène: 17 amino acid peptide near the center of human SIRT3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur SIRT3

Antigène: SIRT3 (Sirtuin 3 (SIRT3))

Autre désignation: SIRT3 (SIRT3 Produits)

Synonymes: anticorps zgc:158774, anticorps sirtuin, anticorps SIR2L3, anticorps 2310003L23Rik, anticorps AI848213, anticorps Sir2l3, anticorps sirtuin 3, anticorps sirt3, anticorps SIRT3, anticorps Sirt3

Sujet: The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence, lifespan extension and several age-related diseases. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) and SIRT3 is the only sirtuin whose increased expression has been shown to correlate with an extended life span in humans. It is localized in the mitochondrial matrix, where it regulates the acetylation levels of metabolic enzymes, including acetyl coenzyme A synthetase 2. SIRT3 is stress-responsive and its increased expression protects myocytes from genotoxic and oxidative stress-mediated cell death.Synonyms: NAD-dependent deacetylase sirtuin-3 mitochondrial, SIR2-like protein 3, SIR2L3, SIRT-3, hSIRT3, sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae), sirtuin 3, sirtuin type 3, sirtuin-3

ID gène: 23410

NCBI Accession: NP_001017524

UniProt: Q9NTG7