ZEB1 anticorps (Center)

N° du produit ABIN783631

Cet anticorps Lapin Polyclonal détecte spécifiquement ZEB1 dans WB, IF et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour ZEB1 anticorps (Center) (ABIN783631)

Antigène: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZEB1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-ZEB1 anticorps

Épitope: Center

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Affinity chromatography purified via peptide column

Immunogène: 15 amino acid peptide near the center of human ZEB1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur ZEB1

Antigène: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Autre désignation: ZEB1

Sujet: ZEB1, initially identified as the delta-crystallin enhancer binding protein delta EF1, is a DNA-binding protein that binds to a modified E-box sequence and has been implicated in postgastrulation embryogenesis. ZEB1 binds to the promoter of several hemapoietic genes, including interleukin-2, CD4, GATA-3, and alpha(4)-integrin, and mice in which ZEB1 has been targeted show thymic atrophy, and severe defects in lymphocyte differentiation. Recent evidence suggests that ZEB1 also regulates the accumulation of adipose tissue and may play a role in obesity. Mutations in this gene have been associated with late-onset Fuchs endothelial corneal dystrophy.Synonyms: AREB6, NIL-2-A, NIL-2-A zinc finger protein, Negative regulator of IL2, TCF-8, TCF8, Transcription factor 8, Zinc finger E-box-binding homeobox 1

ID gène: 6935

NCBI Accession: NP_001121600

UniProt: P37275

Pathways: Regulation of Muscle Cell Differentiation