TCTN1 anticorps (N-Term)

N° du produit ABIN783637

Cet anticorps Lapin Polyclonal détecte spécifiquement TCTN1 dans WB, IF et EIA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour TCTN1 anticorps (N-Term) (ABIN783637)

Antigène: TCTN1 (Tectonic Family Member 1 (TCTN1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TCTN1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-TCTN1 anticorps

Épitope: N-Term

Specificité: This antibody detects TCTN1 . It is predicted to not cross-react with other TCTN members. Multiple isoforms are known to exist, this antibody recognizes isoforms 1 - 3.

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse

Purification: Affinity chromatography purified via peptide column

Immunogène: 15 amino acid peptide near the amino terminus of human TCTN1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur TCTN1

Antigène: TCTN1 (Tectonic Family Member 1 (TCTN1))

Autre désignation: Tectonic-1

Sujet: TCTN1 is the founding member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube. During embryonic development, TCTN1 is expressed in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node. Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator. At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.Synonyms: TCTN1, TECT1

ID gène: 79600

NCBI Accession: NP_001076006

UniProt: Q2MV58

Pathways: Tube Formation