CRISP2 anticorps (N-Term)
Aperçu rapide pour CRISP2 anticorps (N-Term) (ABIN783679)
Antigène
Voir toutes CRISP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Specificité
- This antibody detects CRISP2 at N-term.
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Réactivité croisée (Details)
- Species reactivity (tested):Human
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Purification
- Affinity chromatography purified via peptide column
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Immunogène
- 15 amino acid peptide near the amino terminus of human CRISP2
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- PBS containing 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- CRISP2 (Cysteine-Rich Secretory Protein 2 (CRISP2))
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Autre désignation
- CRISP2
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Sujet
- The cysteine-rich secretory proteins (CRISP) family is a group of four proteins that are strongly expressed in the male reproductive tract and have been implicated in having roles in male fertility. CRISP2, also known as TPX1, has been implicated in the adhesion between spermatids and Sertoli cells, and with CRISP1, is thought to be involved in sperm-egg fusion. CRISP2 has been shown to regulate the Ca2+ influx through ryanodine receptors (RYR) and may influence the acrosome reaction or sperm motility. CRISP2 has also been shown to bind to the mitogen-activated protein kinase kinase kinase 11 (MAP3K11) and localizes to the developing acrosome, suggesting this CRISP2-MAP3K11 complex may have a role in acrosome development.Synonyms: CRISP-2, CT36, Cancer/testis antigen 36, Cysteine-rich secretory protein 2, GAPDL5, TPX1, Testis-specific protein TPX-1
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ID gène
- 7180
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NCBI Accession
- NP_001135879
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UniProt
- P16562
Antigène
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