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NALP8 anticorps (N-Term)

L’anticorps Lapin Polyclonal anti-NALP8 a été validé pour WB, IHC (p) et EIA. Il convient pour détecter NALP8 dans des échantillons de Humain.
N° du produit ABIN783713

Aperçu rapide pour NALP8 anticorps (N-Term) (ABIN783713)

Antigène

Voir toutes NALP8 (NLRP8) Anticorps
NALP8 (NLRP8) (NLR Family, Pyrin Domain Containing 8 (NLRP8))

Reactivité

Humain

Hôte

  • 2
  • 1
Lapin

Clonalité

  • 3
Polyclonal

Conjugué

  • 3
Cet anticorp NALP8 est non-conjugé

Application

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Épitope

    • 2
    • 1
    • 1
    N-Term

    Specificité

    This antibody detects NALP8 at N-term. This antibody is predicted to not cross-react with other NALP family members.

    Réactivité croisée (Details)

    Species reactivity (tested):Human.

    Purification

    Affinity Chromatography purified via peptide column

    Immunogène

    16 amino acid peptide near the amino terminus of Human NALP8
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    PBS containing 0.02 % Sodium Azide as preservative

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène

    NALP8 (NLRP8) (NLR Family, Pyrin Domain Containing 8 (NLRP8))

    Autre désignation

    NALP8

    Sujet

    NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP8 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It maps to chromosome 19q13.42 and is thought to be expressed in testis and ovary, suggesting that NALP8 may be involved in reproduction. Surprisingly, NALP8 seems to be universal in mammals except for rodents, suggesting that the gene may have been lost during evolution.Synonyms: LRR and PYD domains-containing protein 8, NACHT, NLRP8, NOD16, PAN4, PYRIN and NACHT-containing protein 4

    ID gène

    126205

    NCBI Accession

    NP_789781

    UniProt

    Q86W28

    Pathways

    Inflammasome
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