NLRP10 anticorps (N-Term)

N° du produit ABIN783715

Cet anticorps Lapin Polyclonal détecte spécifiquement NLRP10 dans WB et EIA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour NLRP10 anticorps (N-Term) (ABIN783715)

Antigène: NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP10 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-NLRP10 anticorps

Épitope: N-Term

Specificité: This antibody detects NALP10 at N-term.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Affinity chromatography purified via peptide column

Immunogène: 14 amino acid peptide near the amino terminus of human NALP10

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur NLRP10

Antigène: NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))

Autre désignation: NLRP10

Sujet: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP10 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It was initially identified as PYNOD, an Apaf-1-like protein that binds to ASC, caspase-1 and IL-1b, inhibiting the autoprocessing of caspase-1, caspase-1-mediated IL-1b processing, and ASC aggregation. NALP10 is thus a potent regulator of apoptosis and inflammation.Synonyms: NACHT LRR and PYD domains-containing protein 10, NALP10, NOD8, Nucleotide-binding oligomerization domain protein 8, PYNOD

ID gène: 338322

NCBI Accession: NP_789791

UniProt: Q86W26

Pathways: Inflammasome