TCF12 anticorps (N-Term)
Aperçu rapide pour TCF12 anticorps (N-Term) (ABIN783743)
Antigène
Voir toutes TCF12 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Specificité
- This antibody detects TCF12 at N-term.
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Réactivité croisée (Details)
- Species reactivity (tested):Human, mouse, rat
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Purification
- Affinity chromatography purified via peptide column
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Immunogène
- 19 amino acid peptide near the amino terminus of human TCF12
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- PBS containing 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- TCF12 (Transcription Factor 12 (TCF12))
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Autre désignation
- TCF12
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Sujet
- TCF12, also known as HTF4, is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. TCF12 is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. TCF12, in combination with E2A, is required to block thymocyte proliferation prior to pre-TCR expression and is critical for proper T cell differentiation. Recent reports have shown that TCF12 is also a critical factor required for the development of invariant natural killer T cells.Synonyms: DNA-binding protein HTF4, E-box-binding protein, HEB, HTF-4, HTF4, Transcription factor 12, Transcription factor HTF-4
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ID gène
- 6938
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NCBI Accession
- NP_003196
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UniProt
- Q99081
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Pathways
- SARS-CoV-2 Protein Interactome
Antigène
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