EFCAB4B anticorps (C-Term)

N° du produit ABIN783785

Détail du produit anti-EFCAB4B anticorps

Antigène: EFCAB4B (EF-Hand Calcium Binding Domain 4B (EFCAB4B))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EFCAB4B est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects EFCAB4B at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse

Purification: Affinity chromatography purified via peptide column

Immunogène: 14 amino acid peptide near the carboxy terminus of human EFCAB4B

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur EFCAB4B

Antigène: EFCAB4B (EF-Hand Calcium Binding Domain 4B (EFCAB4B))

Autre désignation: EFCAB4B (EFCAB4B Produits)

Synonymes: anticorps CRACR2A, anticorps Gm1073, anticorps Gm462, anticorps calcium release activated channel regulator 2A, anticorps CRACR2A, anticorps Cracr2a

Sujet: EFCAB4B, also known as Calcium release-activated calcium channel regulator 2A, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation. EFCAB4B acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration. A closely related protein, EFCAB4A, is likely to play a similar role as EFCAB4B, but the detailed function of EFCAB4A is still under investigation.Synonyms: EF-hand calcium-binding domain-containing protein 4B, MGC4266

ID gène: 84766

NCBI Accession: NP_001138430

UniProt: Q9BSW2