ANAPC13 anticorps (Center)

N° du produit ABIN783826

Cet anticorps Lapin Polyclonal détecte spécifiquement ANAPC13 dans WB et EIA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour ANAPC13 anticorps (Center) (ABIN783826)

Antigène: ANAPC13 (Anaphase Promoting Complex Subunit 13 (ANAPC13))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANAPC13 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-ANAPC13 anticorps

Épitope: Center

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogène: 17 amino acid peptide near the center of human APC13

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur ANAPC13

Antigène: ANAPC13 (Anaphase Promoting Complex Subunit 13 (ANAPC13))

Autre désignation: ANAPC13

Sujet: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC13 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. APC13 promotes the stable association of APC3/Cdc27 and APC6/Cdc16 with the APC/C.Synonyms: Anaphase-promoting complex subunit 13, Cylosome subunit 13

ID gène: 25847

NCBI Accession: NP_056206

UniProt: Q9BS18