TIE1 anticorps (C-Term)
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- Antigène Voir toutes TIE1 Anticorps
- TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TIE1 est non-conjugé
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- This antibody reacts to the C-term of Protein Tyrosine Kinase Receptor TIE1.
- Purification
- Immunoaffinity Chromatography
- Immunogène
- Synthetic peptide corresponding to C-terminal of human Tie-1 Genename: TIE1
- Isotype
- IgG
- Top Product
- Discover our top product TIE1 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 10 mM PBS, pH 7.4 containing BSA as stabilizer and 0,09 % sodium azide as preservative
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
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- Antigène
- TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
- Autre désignation
- TIE1 (TIE1 Produits)
- Synonymes
- anticorps JTK14, anticorps TIE, anticorps D430008P04Rik, anticorps tie-1, anticorps tyrosine kinase with immunoglobulin like and EGF like domains 1, anticorps tyrosine kinase with immunoglobulin-like and EGF-like domains 1, anticorps tyrosine-protein kinase receptor Tie-1, anticorps endothelium-specific receptor tyrosine kinase 1, anticorps TIE1, anticorps Tie1, anticorps CpipJ_CPIJ018933, anticorps tie1
- Sujet
- TIE1 is a receptor that is implicated in vessel maturation and angiogenesis. TIE1 contains immunoglobulin-like loops and epidermal growth factor (EGF) homology domains. TIE1/TIE (tyrosine kinase with Ig and EGF homology domains 1) and TIE2/Tek define a new class of the receptor tyrosine kinase (RTK) subfamily with unique structural characteristics: two immunoglobulin like domains flanking three epidermal growth factor (EFG) like domains followed by three fibronectin type III like repeats in the extracellular region and a split tyrosine kinase domain in the cytoplasmic region. Human TIE1 cDNA encodes a 1138 amino acid residue precursor protein with a putative signal peptide, an extracellular domain, and a cytoplasmic domain. TIE1 and TIE2, expressed primarily on endothelial and hematopoietic progenitor cells, play important roles in angiogenesis, vasculogenesis, and hematopoiesis. In developing vascular endothelial cells, TIE1 and TIE2 are specifically expressed. Two ligands that bind TIE have been identified, angiopoietin 1 and angiopoietin 2. Based on gene targeting studies, the in vivo functions of TIE1 are related to endothelial cell differentiation.Synonyms: TIE, Tie-1, Tyrosine-protein kinase receptor Tie-1
- ID gène
- 7075
- NCBI Accession
- NP_005415
- Pathways
- Signalisation RTK
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