ITIH4 anticorps (C-Term)

N° du produit ABIN783974

L’anticorps anti-ITIH4 Polyclonal Chèvre est utilisé pour la détection de ITIH4 dans des échantillons de Humain. Il a été validé pour WB, IHC (p) et EIA.

Aperçu rapide pour ITIH4 anticorps (C-Term) (ABIN783974)

Antigène: ITIH4 (Inter alpha Globulin Inhibitor H4 (ITIH4))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp ITIH4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-ITIH4 anticorps

Épitope: AA 890-903, C-Term

Séquence: C-SDDGRRTLRV QGND

Specificité: This antibody is expected to recognize both reported isoforms (NP_002209.2, NP_001159921.1).

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide with sequence from the C Terminus of the protein sequence according to NP_002209.2 and NP_001159921.1. Genename: ITIH4

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ITIH4

Antigène: ITIH4 (Inter alpha Globulin Inhibitor H4 (ITIH4))

Autre désignation: ITIH4

Sujet: The inter-a-trypsin inhibitor (ITI, IaI) family, a typical and classical example for protein-glycosaminoglycanprotein (PGP) complexes, occurs constitutively in plasma at relatively high concentrations and is a result of alternate combinations of three kinds of heavy chains with a common light chain, the bikunin proteoglycan. Bikunin has two proteinase inhibitor domains and belongs to the Kunitz-type protease inhibitor family, it displays an inhibitory activity against trypsin, leukocyte elastase and plasmin. The heavy chains do not have any protease inhibitory properties but have the capacity to interact in vitro and in vivo with hyaluronic acid and this binding promotes the stability of the extra-cellular matrix. The ITI protein family is suspected of playing a key role in the extra-cellular matrix biology.Synonyms: Gp120, IHRP, ITI heavy chain H4, ITI-HC4, ITIHL1, Inter-alpha-inhibitor heavy chain 4, Inter-alpha-trypsin inhibitor family heavy chain-related protein, Inter-alpha-trypsin inhibitor heavy chain H4, PK120, Plasma kallikrein sensitive glycoprotein 120

ID gène: 216

NCBI Accession: NP_002209

Pathways: Glycosaminoglycan Metabolic Process