Annexin VII anticorps (AA 122-419)

N° du produit ABIN783992

L’anticorps anti-Annexin VII Polyclonal Lapin est utilisé pour la détection de Annexin VII dans des échantillons de Humain, Souris, Rat et Boeuf (Vache). Il a été validé pour WB et IHC (p).

Aperçu rapide pour Annexin VII anticorps (AA 122-419) (ABIN783992)

Antigène: Annexin VII (ANXA7) (Annexin A7 (ANXA7))

Reactivité: Humain, Souris, Rat, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Annexin VII est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Annexin VII anticorps

Épitope: AA 122-419

Specificité: Recognizes Annexin A7.

Réactivité croisée (Details): Species reactivity (expected):Mouse (94 %), Rat (94 %), Cow (93 %)Species reactivity (tested):Human.

Purification: Antigen-Affinity Chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 122 and 419 of Human Annexin VII

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.28 mg/mL

Buffer: 0.1 M Tris, 0.1 M Glycine, 10 % Glycerol ( pH 7) containing 0.01 % Thimerosal as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at -20 °C.

Détails sur Annexin VII

Antigène: Annexin VII (ANXA7) (Annexin A7 (ANXA7))

Autre désignation: Annexin A7 / ANXA7

Sujet: Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion.Synonyms: ANX7, Annexin VII, Annexin-7, SNX, Synexin

ID gène: 310, 9606