RGS4 anticorps (AA 1-188)

N° du produit ABIN783994

Cet anticorps Lapin Polyclonal détecte spécifiquement RGS4 dans WB et IHC (p). Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Lapin, Mouton et Porc.

Aperçu rapide pour RGS4 anticorps (AA 1-188) (ABIN783994)

Antigène: RGS4 (Regulator of G-Protein Signaling 4 (RGS4))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Mouton, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RGS4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-RGS4 anticorps

Épitope: AA 1-188

Specificité: Recognizes RGS4

Réactivité croisée (Details): Species reactivity (expected):Cow (97 %), Rat (97 %), Rabbit (96 %), Pig (96 %), Sheep (97 %)Species reactivity (tested):Human, Mouse.

Purification: Antigen-Affinity Chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 188 of Human RGS4

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.43 mg/mL

Buffer: 0.1 M Tris, 0.1 M Glycine, 20 % Glycerol ( pH 7) containing 0.01 % Thimerosal as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at -20 °C.

Détails sur RGS4

Antigène: RGS4 (Regulator of G-Protein Signaling 4 (RGS4))

Autre désignation: RGS4

Sujet: Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37 % identical to RGS1 and 97 % identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]Synonyms: RGP4, Regulator of G-protein signaling 4

ID gène: 5999

NCBI Accession: NP_005604

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling