TPX2 anticorps (Internal Region)
Aperçu rapide pour TPX2 anticorps (Internal Region) (ABIN784231)
Antigène
Voir toutes TPX2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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Specificité
- This aAntibody detects endogenous levels of total TPX2 protein.
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Réactivité croisée (Details)
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human. -
Purification
- Immunoaffinity Chromatography.
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Immunogène
- Synthetic peptide - KLH conjugated Remarks: Antigen Modification: Internal
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS (without Mg2+, Ca2+), pH 7.4, 150 mM Sodium Chloride, 0.02 % Sodium Azide and 50 % Glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))
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Autre désignation
- TPX2 / DIL2
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Sujet
- TPX2 is a spindle assembly factor, required for normal assembly of mitotic spindles, for normal assembly of microtubules during apoptosis, and for chromatin and/or kinetochore dependent microtubule nucleation. TPX2 mediates AURKA localization to spindle microtubules, activates AURKA by promoting its autophosphorylation at 'Thr-288', and protects this residue against dephosphorylation.Synonyms: C20orf1, C20orf2, DIL-2, Differentially expressed in cancerous and non-cancerous lung cells 2, HCA519, Hepatocellular carcinoma-associated antigen 519, Restricted expression proliferation-associated protein 100, Targeting protein for Xklp2
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ID gène
- 22974
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NCBI Accession
- NP_036244
Antigène
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