ENOS anticorps (AA 1181-1194)
Aperçu rapide pour ENOS anticorps (AA 1181-1194) (ABIN784232)
Antigène
Voir toutes ENOS (NOS3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1181-1194
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Séquence
- CQERQLRGAV PWAFD Remarks: The immunizing sequence has 10/11 identical amino acids in Mouse, Guinea Pig, Bovine, Porcine, Rat and Canine. Antigen Modificati on: aa1181-1194
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Specificité
- Recognizes eNOS/NOS III, Mr ~135 kDa.
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Réactivité croisée (Details)
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Species reactivity (expected):Bovine, Dog, Guinea pig, Mouse, Porcine, Rat.
Species reactivity (tested):Human. -
Purification
- Protein A Chromatography.
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Immunogène
- kLH-conjugated, synthetic peptide corresponding to amino acids 1181-1194 of Human eNOS/NOS III.
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.6, 0.07 % Sodium Azide, before the addition of Glycerol to 30 %.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))
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Autre désignation
- NOS3
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Sujet
- Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: Constitutive NOS, EC-NOS, Endothelial NOS, NOS type III, Nitric oxide synthase, eNOS, endothelial
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ID gène
- 4846
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NCBI Accession
- NP_000594
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Pathways
- ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Response to Molecule of Bacterial Origin, Myometrial Relaxation and Contraction, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
Antigène
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