IL12A anticorps

N° du produit ABIN784573

Détail du produit anti-IL12A anticorps

Antigène: IL12A (Interleukin 12 alpha (IL12A))

Reactivité: Humain, Chien, Porc

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp IL12A est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: Recognizes Interleukin-12 alpha / IL12A.

Réactivité croisée (Details): Species reactivity (expected):Canine (Dog), Pig.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogène: Synthetic peptide - KLH conjugated of Human IL12A

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid freeze-thaw cycles.

Détails sur IL12A

Antigène: IL12A (Interleukin 12 alpha (IL12A))

Autre désignation: Interleukin-12 alpha / IL12A (IL12A Produits)

Synonymes: anticorps CLMF, anticorps IL-12A, anticorps NFSK, anticorps NKSF1, anticorps P35, anticorps CLMF2, anticorps IL-12B, anticorps NKSF, anticorps NKSF2, anticorps p40, anticorps Il-12b, anticorps Il12p40, anticorps Il-12p40, anticorps Il12, anticorps IL-12p40, anticorps IL-12p35, anticorps Il-12a, anticorps Ll12a, anticorps p35, anticorps IL12p35, anticorps Il-12 p35, anticorps IL12p40, anticorps IL12, anticorps IL-12 p35, anticorps interleukin 12A, anticorps interleukin 12B, anticorps interleukin 12b, anticorps interleukin 12a, anticorps Interleukin 12 level, anticorps IL12A, anticorps IL12B, anticorps Il12b, anticorps Il12a, anticorps IL12, anticorps il12a

Sujet: Interleukin 12 (IL12) can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine activated killer cells, and stimulate the production of IFN gamma by resting PBMC. IL12 induces IFN gamma, TNF alpha production in T and NK cells, costimulation of PBL proliferation, proliferation/differentiation of TH1 T lymphocytes. It is downregulated by IL10, homodimeric p40 antagonistic to functional p70 heterodimer. IL12R beta 1 binds p40 but when dimeric with IL12R beta 2 binds p35.Synonyms: CLMF p35, Cytotoxic lymphocyte maturation factor 35 kDa subunit, IL-12 subunit p35, IL-12A, NK cell stimulatory factor chain 1, NKSF1

ID gène: 3592

NCBI Accession: NP_000873

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation