DARC anticorps (N-Term)

N° du produit ABIN784594

Cet anticorps Lapin Polyclonal détecte spécifiquement DARC dans IF, IHC (p) et EIA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour DARC anticorps (N-Term) (ABIN784594)

Antigène: DARC (Duffy Blood Group, Chemokine Receptor (DARC))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DARC est non-conjugé

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-DARC anticorps

Épitope: N-Term

Specificité: This antibody detects endogenous levels of total CD234 protein.

Purification: Immunoaffinity Chromatography

Immunogène: Synthetic peptide from human DARC. Remarks: Antigen Modification: N-Terminus

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS (without Mg2+, Ca2+), pH 7.4, 150 mM Sodium Chloride, 0.02 % Sodium Azide and 50 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C or lower. Avoid freeze-thaw cycles.

Détails sur DARC

Antigène: DARC (Duffy Blood Group, Chemokine Receptor (DARC))

Autre désignation: CD234 / DARC

Sujet: Duffy blood group antigens, part of the Chemokine Receptor family, appear to be multimeric erythrocyte-membrane protein receptors composed of different subunits. A glycoprotein, GPD, is the major subunit of the protein complex. Other components include the Rh, PGM1, Fy, and PEPC proteins. Duffy antigen is expressed by red blood cells, by postcapillary venule endothelium throughout the body, except in the liver, and by Purkinje cells of the cerebellum. Duffy negativity (lack of Duffy expression in bone marrow) has been linked to protection against malaria. In erythrocytes, the chemokines interleukin-8 and melanoma growth stimulatory activity (MGSA) activate Duffy antigen.Synonyms: Duffy antigen/chemokine receptor, FY, Fy glycoprotein, GPD, Glycoprotein D, GpFy, Plasmodium vivax receptor

ID gène: 2532

NCBI Accession: NP_001116423