CD41, CD61 anticorps

N° du produit ABIN784612

Cet anticorps Souris Monoclonal détecte spécifiquement CD41, CD61 dans FACS, IP, EIA, IHC (fro) et Func. Il présente une réactivité envers Humain.

Aperçu rapide pour CD41, CD61 anticorps (ABIN784612)

Antigène: CD41, CD61 (CD41,CD61)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD41, CD61 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Clone: P2

Détail du produit anti-CD41, CD61 anticorps

Immunogène: Human platelets

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 1 mL distilled water.

Concentration: 0.2 mg/mL (prior to lyophilization)

Buffer: PBS buffer with 1 mg/mL BSA as stabilizer without preservatives

Agent conservateur: Without preservative

Stock: 4 °C

Stockage commentaire: Store at 2 - 8 °C.

Détails sur CD41, CD61

Antigène: CD41, CD61 (CD41,CD61)

Sujet: Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.Synonyms: CD41, CD61, GP2B, GP3A, GPIIb, GPIIb-IIIa, GPalpha IIb, ITGA2B, ITGAB, ITGB3, Integrin alpha-IIb, Integrin beta-3, Platelet membrane glycoprotein IIb