CD41, CD61 anticorps
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- Antigène Voir toutes CD41, CD61 Anticorps
- CD41, CD61 (CD41,CD61)
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD41, CD61 est non-conjugé
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Application
- Flow Cytometry (FACS), Immunoprecipitation (IP), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
- Immunogène
- Human platelets
- Clone
- P2
- Isotype
- IgG1
- Top Product
- Discover our top product CD41, CD61 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Reconstitution
- Restore with 1 mL distilled water.
- Concentration
- 0.2 mg/mL (prior to lyophilization)
- Buffer
- PBS buffer with 1 mg/mL BSA as stabilizer without preservatives
- Agent conservateur
- Without preservative
- Stock
- 4 °C
- Stockage commentaire
- Store at 2 - 8 °C.
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- Antigène
- CD41, CD61 (CD41,CD61)
- Abstract
- CD41, CD61 Produits
- Sujet
- Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.Synonyms: CD41, CD61, GP2B, GP3A, GPIIb, GPIIb-IIIa, GPalpha IIb, ITGA2B, ITGAB, ITGB3, Integrin alpha-IIb, Integrin beta-3, Platelet membrane glycoprotein IIb
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