LRP6 anticorps (pThr1479) (Cy5)

N° du produit ABIN801637

Cet anticorps Lapin Polyclonal détecte spécifiquement LRP6 dans WB, IF (p), IF (cc) et FACS. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour LRP6 anticorps (pThr1479) (Cy5) (ABIN801637)

Antigène: LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRP6 est conjugé à/à la Cy5

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Flow Cytometry (FACS)

Détail du produit anti-LRP6 anticorps (Cy5)

Épitope: pThr1479

Réactivité croisée: Humain, Souris

Homologie: Dog,Cow,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human LRP6 around the phosphorylation site of Thr1479

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur LRP6

Antigène: LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))

Autre désignation: LRP6

Sujet:

Synonyms: LRP6 Thr1479, LRP6 T1479, p-LRP6 Thr1479, p-LRP6 T1479, ADCAD2, C030016K15Rik, Cd, FLJ90062, FLJ90421, Low density lipoprotein receptor related protein 6, LRP6_HUMAN, Low-density lipoprotein receptor-related protein 6, low-density lipoprotein receptor-related protein 6 precursor, LRP-6.

Background: This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009].

ID gène: 4040

UniProt: O75581

Pathways: Signalisation WNT, Tube Formation