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MCAM anticorps (pTyr641)

MCAM Reactivité: Humain, Rat WB, ELISA Hôte: Lapin Polyclonal unconjugated

N° du produit ABIN802563

Fiche de données

Antigène Voir toutes MCAM Anticorps

MCAM (Melanoma Cell Adhesion Molecule (MCAM))
Épitope
16

13

10

6

4

4

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pTyr641
Reactivité
128

54

47

15

14

9

8

6

5

2
Humain, Rat
Hôte
92

56

8

1

1

1
Lapin
Anticorps secondaires appropriés
Clonalité
86

73
Polyclonal
Conjugué
72

13

12

9

6

5

4

4

4

3

3

3

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp MCAM est non-conjugé
Application
90

75

68

44

23

17

15

10

7

5

4

4

3

3

2

1

1

1

1
Western Blotting (WB), ELISA

Réactivité croisée

Humain, Souris

Purification

Purified by Protein A.

Immunogène

KLH conjugated synthetic phosphopeptide derived from human MCAM around the phosphorylation site of Tyr641

Isotype

IgG

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anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 201-300) antibody
MCAM Reactivité: Humain, Rat FACS, WB, ELISA, IHC (p) Hôte: Lapin Polyclonal unconjugated

Indications d'application

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur

ProClin

Précaution d'utilisation

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock

4 °C,-20 °C

Stockage commentaire

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption

12 months
Antigène

MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Autre désignation

MCAM (MCAM Produits)

Synonymes

anticorps CD146, anticorps MUC18, anticorps Muc18, anticorps 1-gicerin, anticorps AV025631, anticorps CD149, anticorps s-endo, anticorps s-gicerin, anticorps cd146, anticorps gicerin, anticorps id:ibd3512, anticorps mcam, anticorps MCAM, anticorps melanoma cell adhesion molecule, anticorps melanoma cell adhesion molecule b, anticorps MCAM, anticorps Mcam, anticorps mcamb

Sujet

Synonyms: Cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, Melanoma cell adhesion molecule, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, S-endo 1 endothelial-associated antigen, MCAM, MUC18
Background: Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.

ID gène

4162