Aquaporin 1 anticorps (N-Term)
Aperçu rapide pour Aquaporin 1 anticorps (N-Term) (ABIN863206)
Antigène
Voir toutes Aquaporin 1 (AQP1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- N-Term
-
Specificité
- Detects ~28.5 kDa. May detect larger glycosylated bands ~35-50 kDa.
-
Réactivité croisée
- Humain, Souris, Rat
-
Purification
- Protein A Purified
-
Immunogène
- Produced against the N-terminal peptide (sequence N-MASEFKKKLF) of rat Aquaporin 1
-
-
-
-
Indications d'application
-
- WB (1:2000)
- IHC (1:200)
- ICC/IF (1:400)
- optimal dilutions for assays should be determined by the user.
-
Commentaires
-
0.5 μg/ml of ABIN863206 was sufficient for detection of aquaporin 1 in 10 μg of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- -20°C
-
-
- Aquaporin 1 (AQP1) (Aquaporin 1 (Colton Blood Group) (AQP1))
-
Autre désignation
- Aquaporin 1
-
Sujet
- Aquaporins selectively conduct water molecules in and out of the cell, while preventing the passage of ions and other solutes. Known as water channels, they are integral membrane pore proteins (1, 2). Aquarporin 1 is a widely expressed water channel, found in the basolateral and apical plasma membranes of the proximal tubes, the descending loop of Henel and in the descending portion of the vasa recta. Additionally it is found in red blood cells, vascular endothelium, gastrointestinal tract, sweat glands and lungs. It is not regulated by vasopressin (3).
-
ID gène
- 25240
-
NCBI Accession
- NP_036910
-
UniProt
- P29975
-
Pathways
- Hormone Transport
Antigène
-