APOE anticorps
Aperçu rapide pour APOE anticorps (ABIN865413)
Antigène
Voir toutes APOE AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Purification
- Ascitic fluid
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Immunogène
- Purified recombinant fragment of human ApoE expressed in E. Coli.
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Isotype
- IgG1
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Indications d'application
- WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, FC: 1/200 - 1/400 ELISA: Propose dilution 1/10000.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 100g/100l
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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- APOE (Apolipoprotein E (APOE))
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Autre désignation
- ApoE
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Sujet
- Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Synonyms: AD2, LPG, LDLCQ5, MGC1571
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Poids moléculaire
- 36kDa
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ID gène
- 348
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Pathways
- Regulation of Cell Size, Lipid Metabolism
Antigène
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