KDM3A anticorps

N° du produit ABIN865496

L’anticorps anti-KDM3A Monoclonal Souris est utilisé pour la détection de KDM3A dans des échantillons de Humain. Il a été validé pour WB, ELISA et IF.

Aperçu rapide pour KDM3A anticorps (ABIN865496)

Antigène: KDM3A (Lysine (K)-Specific Demethylase 3A (KDM3A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KDM3A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 2E1

Détail du produit anti-KDM3A anticorps

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human KDM3A expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: WB: 1/500 - 1/2000, IF: 1/200 - 1/1000, ELISA: Propose dilution 1/10000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100g/100l

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur KDM3A

Antigène: KDM3A (Lysine (K)-Specific Demethylase 3A (KDM3A))

Autre désignation: KDM3A

Sujet: This gene encodes a zinc finger protein that contains a jumonji domain and may play a role in hormone-dependent transcriptional activation. JMJD1A functions as a mono- and dimethylation-specific demethylase, binding iron and -ketoglutarate as cofactors and demethylating Lysine 9 of Histone H3. This suggests that JMJD1A plays a central role in the histone code and participates in nuclear hormone receptor-based transcriptional regulation. In addition, JMJD1A plays an important role in the regulation of cell growth during development and in chromatin regulation. JMJD1A directly regulates the expression of TNP1 and Protamine 1 (proteins required for the proper packaging and condensation of sperm chromatin) and, therefore, plays an essential role in spermatogenesis. Synonyms: TSGA, JMJD1, JHDM2A, JHMD2A, JMJD1A, KIAA0742, DKFZp686A24246, DKFZp686P07111, KDM3A

Poids moléculaire: 147kDa

ID gène: 55818

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, L'effet Warburg