Neuropilin 1 anticorps

N° du produit ABIN866080

Cet anticorps Souris Monoclonal détecte spécifiquement Neuropilin 1 dans WB et ICC. Il présente une réactivité envers Souris.

Aperçu rapide pour Neuropilin 1 anticorps (ABIN866080)

Antigène: Neuropilin 1 (NRP1)

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Neuropilin 1 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Clone: 10-D9

Détail du produit anti-Neuropilin 1 anticorps

Specificité: This antibody is produced by immunizing mouse with recombinant protein Neuropilin-1.

Réactivité croisée: Souris

Attributs du produit: Positive Control: Recombinant protein. Cellular Localization: Cell membrane, secretory protein

Isotype: IgM

Information d'application

Indications d'application: WB 1:1,000~1:2,000. ICC 1:100~1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.17mg/ml

Buffer: 1xTBS (pH7.4), 0.5% BSA, 25% Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur Neuropilin 1

Antigène: Neuropilin 1 (NRP1)

Autre désignation: Neuropilin-1

Sujet: Neuropilin-1 is a single-pass type I membrane protein, which has two isoforms. The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. The soluble isoform 2 binds VEGF-165 (vascular endothelial growth factor165) and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. Its expression has an averse effect on blood vessel number and integrity.

Poids moléculaire: 47kDa

UniProt: P97333

Pathways: Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals