CD22 anticorps (AA 839-843)

N° du produit ABIN871688

L’anticorps anti-CD22 Polyclonal Lapin est utilisé pour la détection de CD22 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour CD22 anticorps (AA 839-843) (ABIN871688)

Antigène: CD22 (CD22 Molecule (CD22))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD22 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CD22 anticorps

Épitope: AA 839-843

Specificité: The antibody detects endogenous level of total CD22 protein.

Purification: Affinity purified

Immunogène: Peptide sequence around AA 839-843 (N-V-D-Y-V) derived from Human CD22. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Information d'application

Indications d'application: Western blotting: 1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur CD22

Antigène: CD22 (CD22 Molecule (CD22))

Autre désignation: CD22

Sujet: Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins, one of which is CD45. Preferentially binds to a-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.

Poids moléculaire: 140 kDa

ID gène: 933

NCBI Accession: NP_001762

UniProt: P20273