Crossover junction endonuclease EME1 (EME1) (AA 412-500) anticorps

N° du produit ABIN873042

Cet anticorps anti-Crossover junction endonuclease EME1 Polyclonal Lapin (ABIN873042) détecte spécifiquement Crossover junction endonuclease EME1 dans WB, IHC (p), IHC (fro), IF (cc) et IF (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Crossover junction endonuclease EME1 (EME1) (AA 412-500) anticorps (ABIN873042)

Antigène: Crossover junction endonuclease EME1 (EME1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit

Épitope: AA 412-500

Fonction: EME1 Polyclonal Antibody

Homologie: Human,Mouse,Rat,Dog,Sheep,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human EME1

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-5000),

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Crossover junction endonuclease EME1 (EME1)

Autre désignation: EME1

Sujet:

Synonyms: Crossover junction endonuclease EME1, Eme1 essential meiotic endonuclease 1 homolog 1 S. pombe, EME1, S. pombe, homolog of, 1, essential meiotic endonuclease 1 homolog 1 S pombe, Essential Meiotic Endonuclease 1 Homolog 1, essential meiotic endonuclease 1 homolog 2, Essential meiotic endonuclease 1, S. pombe, homolog of, 1, hMMS4, homolog of yeast EME1 endonuclease, MMS4, MMS4 homolog, MMS4L, EME1_HUMAN.

Background: EME1 complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein (MUS81) to form an endonuclease complex which cleaves branched DNA structures, especially those arising during stalled DNA replication. The protein may be involved in repairing DNA damage and in maintaining genomic stability. It interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. Alternative splicing results in multiple transcript variants.

ID gène: 146956