MAP3K9 anticorps (pThr312) (Biotin)

N° du produit ABIN877898

L’anticorps Lapin Polyclonal anti-MAP3K9 a été validé pour WB, ELISA, IHC (p) et IHC (fro). Il convient pour détecter MAP3K9 dans des échantillons de Humain et Rat.

Aperçu rapide pour MAP3K9 anticorps (pThr312) (Biotin) (ABIN877898)

Antigène: MAP3K9 (Mitogen-Activated Protein Kinase Kinase Kinase 9 (MAP3K9))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP3K9 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-MAP3K9 anticorps (Biotin)

Épitope: pThr312

Réactivité croisée: Humain, Rat

Homologie: Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human MAP3K9 around the phosphorylation site of Thr312

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur MAP3K9

Antigène: MAP3K9 (Mitogen-Activated Protein Kinase Kinase Kinase 9 (MAP3K9))

Autre désignation: MAP3K9+

Sujet:

Synonyms: MLK1, MEKK9, PRKE1, Mitogen-activated protein kinase kinase kinase 9, Mixed lineage kinase 1, MAP3K9

Background: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.

ID gène: 4293

UniProt: P80192