ALOXE3 anticorps (AA 141-240) (AbBy Fluor® 647)

N° du produit ABIN882258

Cet anticorps anti-ALOXE3 est un anticorps Lapin Polyclonal détectant ALOXE3 dans IF (cc) et IF (p). Adapté pour Humain.

Aperçu rapide pour ALOXE3 anticorps (AA 141-240) (AbBy Fluor® 647) (ABIN882258)

Antigène: ALOXE3 (Arachidonate Lipoxygenase 3 (ALOXE3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALOXE3 est conjugé à/à la AbBy Fluor® 647

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-ALOXE3 anticorps (AbBy Fluor® 647)

Épitope: AA 141-240

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ALOXE3

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur ALOXE3

Antigène: ALOXE3 (Arachidonate Lipoxygenase 3 (ALOXE3))

Autre désignation: ALOXE3

Sujet:

Synonyms: ALOXE3, Arachidonate lipoxygenase 3, e LOX 3, E LOX, e-LOX-3, eLOX3, Epidermal lipoxygenase, Epidermis-type lipoxygenase 3, Lipoxygenase 3, LOXE3_HUMAN.

Background: Introduces molecular oxygen into polyunsaturated fatty acids. Exact substrate is not known.Tissue specificity:Predominantly expressed in skin.Involvement in diseaseDefects in ALOXE3 are a cause of non-bullous congenital ichthyosiform erythroderma (NCIE). NCIE is a non-bullous ichthyosis, a skin disorder characterized by abnormal cornification of the epidermis. Most affected individuals are born with a tight, shiny, translucent covering called collodion membrane. The collodion membrane subsequently evolves into generalized scaling and intense redness of the skin. Clinical features are milder than in lamellar ichthyoses and demonstrate a greater variability in the intensity of erythema, size and type of scales. In contrast to lamellar ichthyoses, scales are usually white, fine and powdery, and palms and soles are severely affected. Patients suffer from palmoplantar keratoderma, often with painful fissures, digital contractures, and loss of pulp volume.

ID gène: 59344

Pathways: Cell-Cell Junction Organization