BRIP1 anticorps (AbBy Fluor® 647)

N° du produit ABIN884389

Cet anticorps Lapin Polyclonal détecte spécifiquement BRIP1 dans IF (p). Il présente une réactivité envers Humain, Souris, Rat, Poulet, Boeuf (Vache), Chien, Cheval et Porc.

Aperçu rapide pour BRIP1 anticorps (AbBy Fluor® 647) (ABIN884389)

Antigène: BRIP1 (BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1))

Reactivité: Humain, Souris, Rat, Poulet, Boeuf (Vache), Chien, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BRIP1 est conjugé à/à la AbBy Fluor® 647

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-BRIP1 anticorps (AbBy Fluor® 647)

Specificité: Excitation / Emission Wavelengths: 652nm/668nm

Réactivité croisée: Souris, Rat (Rattus), Lapin, Boeuf (Vache), Porc, Cheval, Chien, Poulet

Purification: Antibodies are purified by protein A and peptide affinity chromatography.

Immunogène: Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human BACH1
Please inquire for sequence information.

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P)(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur BRIP1

Antigène: BRIP1 (BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1))

Autre désignation: BACH1/BRIP1

Sujet: BACH1 is a member of the DEAH helicase family that interacts with BRCA1, in vivo. BACH1 is a DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. BACH1 acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination, and is involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1. The BACH1/BRCA1 complex formation contributes to a key function of BRCA1. Therefore, it is likely that BACH1 is a target of germline cancer-inducing mutations.
Synonym: BACH 1, BRIP1, BACH-1, BRAC 1 Associated C Terminal Helicase 1, BRCA 1 Interacting Protein 1, BRCA1 binding helicase like protein BACH1, BRCA1 interacting protein C terminal helicase 1, BRIP 1, BRIP-1, FANCJ, ATP dependent RNA helicase BRIP1, Fanconi anemia group J protein, FLJ90232, MGC126521, MGC126523, OF antibody Protein FACJ.

Poids moléculaire: 130kDa

ID gène: 571

Pathways: Réparation de l'ADN