CCDC138 anticorps (AA 551-665) (AbBy Fluor® 555)

N° du produit ABIN887230

Cet anticorps Lapin Polyclonal détecte spécifiquement CCDC138 dans WB, IF (cc) et IF (p). Il présente une réactivité envers Humain.

Aperçu rapide pour CCDC138 anticorps (AA 551-665) (AbBy Fluor® 555) (ABIN887230)

Antigène: CCDC138 (Coiled-Coil Domain Containing 138 (CCDC138))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCDC138 est conjugé à/à la AbBy Fluor® 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-CCDC138 anticorps (AbBy Fluor® 555)

Épitope: AA 551-665

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CCDC138

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CCDC138

Antigène: CCDC138 (Coiled-Coil Domain Containing 138 (CCDC138))

Autre désignation: CCDC138

Sujet:

Synonyms: CCDC 138, CCDC138, Coiled coil domain containing 138, Coiled coil domain containing protein 138, coiled-coil domain containing 138, FLJ 32745, FLJ32745, CC138_HUMAN.

Background: CCDC138, also known as FLJ32745, is a 685 amino acid protein expressed as two isoforms produced by alternative splicing. The gene that encodes CCDC138 maps to human chromosome 2q12.3. The second largest human chromosome, chromosome 2 consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes.

ID gène: 165055

Pathways: BCR Signaling