INSRR anticorps (PE)

N° du produit ABIN902841

Cet anticorps anti-INSRR est un anticorps Lapin Polyclonal détectant INSRR dans IF (p). Adapté pour Humain, Souris, Rat, Boeuf (Vache), Chien et Porc.

Aperçu rapide pour INSRR anticorps (PE) (ABIN902841)

Antigène: INSRR (Insulin Receptor-Related Receptor (INSRR))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp INSRR est conjugé à/à la PE

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-INSRR anticorps (PE)

Specificité: Excitation / Emission Wavelengths: 565nm/578nm

Réactivité croisée: Rat (Rattus), Chien, Porc, Boeuf (Vache)

Purification: purified by Protein A

Immunogène: KLH conjugated synthetic peptide derived from human Insulin receptor-related protein beta chain

Isotype: IgG

Information d'application

Commentaires:

Excitation / Emission wavelength: 496nm / 578nm

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 µg/µL

Buffer: Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 4 °C for 12 months

Date de péremption: 12 months

Détails sur INSRR

Antigène: INSRR (Insulin Receptor-Related Receptor (INSRR))

Autre désignation: INSRR

Sujet: The insulin receptor related receptor (IRR) is a heterotetrameric transmembrane receptor composed of two alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain. Member of the insulin RTK family, IRR shares high homology with the insulin (IR) and the insulin-like growth factor-1 receptor (IGF-1R), but doesnﾒt bind any of IR and IGF-1R known ligands. In contrast to the widespread patterns of expression to IR and IGF-1R, IRR demonstrates a very restricted cellular distribution in a subset of tissues of neuronal origin and its biological functions are still unknown.

Poids moléculaire: 144kDa

ID gène: 3645

Pathways: Signalisation RTK