INSRR anticorps (AA 801-900) (HRP)

N° du produit ABIN902843

L’anticorps Lapin Polyclonal anti-INSRR a été validé pour ELISA, IHC (p) et IHC (fro). Il convient pour détecter INSRR dans des échantillons de Humain.

Aperçu rapide pour INSRR anticorps (AA 801-900) (HRP) (ABIN902843)

Antigène: INSRR (Insulin Receptor-Related Receptor (INSRR))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp INSRR est conjugé à/à la HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-INSRR anticorps (HRP)

Épitope: AA 801-900

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Insulin receptor-related protein beta chain

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur INSRR

Antigène: INSRR (Insulin Receptor-Related Receptor (INSRR))

Autre désignation: INSRR

Sujet:

Synonyms: INSRR, Insulin receptor related receptor precursor, IR related receptor, IRR, Sirr, Insulin receptor-related protein, IR-related receptor, Insulin receptor-related protein beta chain, INSRR_HUMAN.

Background: The insulin receptor related receptor (IRR) is a heterotetrameric transmembrane receptor composed of two alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain. Member of the insulin RTK family, IRR shares high homology with the insulin (IR) and the insulin-like growth factor-1 receptor (IGF-1R), but doesn?t bind any of IR and IGF-1R known ligands. In contrast to the widespread patterns of expression to IR and IGF-1R, IRR demonstrates a very restricted cellular distribution in a subset of tissues of neuronal origin and its biological functions are still unknown.

ID gène: 3645

Pathways: Signalisation RTK