KISS1R anticorps (AA 139-157) (AbBy Fluor® 488)

N° du produit ABIN903768

Cet anticorps anti-KISS1R est un anticorps Lapin Polyclonal détectant KISS1R dans WB. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour KISS1R anticorps (AA 139-157) (AbBy Fluor® 488) (ABIN903768)

Antigène: KISS1R (KISS1 Receptor (KISS1R))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KISS1R est conjugé à/à la AbBy Fluor® 488

Application: Western Blotting (WB)

Détail du produit anti-KISS1R anticorps (AbBy Fluor® 488)

Épitope: AA 139-157

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Sheep,Pig,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human KiSS1 receptor

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur KISS1R

Antigène: KISS1R (KISS1 Receptor (KISS1R))

Autre désignation: Kiss1 Receptor

Sujet:

Synonyms: HH8, CPPB1, GPR54, AXOR12, KISS-1R, HOT7T175, KiSS-1 receptor, G-protein coupled receptor 54, G-protein coupled receptor OT7T175, Hypogonadotropin-1, Kisspeptins receptor, Metastin receptor, KISS1R

Background: Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins.

ID gène: 84634

UniProt: Q969F8