NLRP7 anticorps (AA 901-980) (FITC)

N° du produit ABIN908470

Cet anticorps Lapin Polyclonal détecte spécifiquement NLRP7 dans WB, IF (cc) et IF (p). Il présente une réactivité envers Humain.

Aperçu rapide pour NLRP7 anticorps (AA 901-980) (FITC) (ABIN908470)

Antigène: NLRP7 (NLR Family, Pyrin Domain Containing 7 (NLRP7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP7 est conjugé à/à la FITC

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-NLRP7 anticorps (FITC)

Épitope: AA 901-980

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human NLRP7

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur NLRP7

Antigène: NLRP7 (NLR Family, Pyrin Domain Containing 7 (NLRP7))

Autre désignation: NLRP7

Sujet:

Synonyms: CLR19.4, FLJ94610, HYDM, NACHT, leucine rich repeat and PYD containing 7, NACHT, LRR and PYD containing protein 7, NACHT, LRR and PYD domains containing protein 7, NACHT, LRR and PYD domains-containing protein 7, NALP7, NALP7_HUMAN, NLR family, pyrin domain containing 7, NLRP7, NOD12, Nucleotide-binding oligomerization domain protein 12, Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 7, PAN7, PYPAF3, PYRIN-containing APAF1-like protein 3.

Background: This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

ID gène: 199713

Pathways: Inflammasome