PHGDH anticorps (AA 101-200) (HRP)
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- Antigène Voir toutes PHGDH Anticorps
- PHGDH (phosphoglycerate Dehydrogenase (PHGDH))
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Épitope
- AA 101-200
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PHGDH est conjugé à/à la HRP
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human PHGDH
- Isotype
- IgG
- Top Product
- Discover our top product PHGDH Anticorps primaire
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- Indications d'application
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Conseil sur la manipulation
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- PHGDH (phosphoglycerate Dehydrogenase (PHGDH))
- Autre désignation
- PHGDH (PHGDH Produits)
- Synonymes
- anticorps fb38f06, anticorps zgc:65956, anticorps wu:fb38f06, anticorps embryo sac development arrest 9, anticorps F10M10.7, anticorps ECK2909, anticorps JW2880, anticorps 3-PGDH, anticorps 3PGDH, anticorps 4930479N23, anticorps A10, anticorps PGAD, anticorps PGD, anticorps PGDH, anticorps SERA, anticorps PDG, anticorps phosphoglycerate dehydrogenase, anticorps D-3-phosphoglycerate dehydrogenase, anticorps 3-phosphoglycerate dehydrogenase, anticorps phgdh, anticorps EDA9, anticorps serA, anticorps Sthe_2284, anticorps Dacet_1260, anticorps Mrub_0173, anticorps MMAH_RS07650, anticorps Arnit_0487, anticorps Ndas_0174, anticorps Mesil_2386, anticorps Slip_0010, anticorps Trad_0302, anticorps Acear_0027, anticorps Mahau_0665, anticorps MZHIL_RS05165, anticorps Mesop_1331, anticorps Thein_0855, anticorps Phgdh, anticorps PHGDH
- Sujet
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Synonyms: NLS, PDG, PGD, NLS1, PGAD, PGDH, SERA, 3PGDH, 3-PGDH, PHGDHD, HEL-S-113, D-3-phosphoglycerate dehydrogenase, PHGDH, PGDH3
Background: The survival and development of central neurons require the supply of trophic factors by glial cells. The trophic actions of glial cells on Purkinje neurons are mediated by L-serine and glycine, which are glia-derived trophic factors synthesized by 3PGDH (1). 3PGDH protein is 544 amino acids in length. Two distinct mRNA transcripts that encode for 3PGDH protein in normal human tissues are dominant 2.1 kb mRNA, which is highly expressed in prostate, testis, ovary, brain, liver, kidney, and pancreas, and weakly expressed in thymus, colon, and heart, and 710 bp mRNA, which is highly expressed in heart and skeletal muscle (2). 3PGDH is regulated at the transcriptional level depending on tissue specificity and cellular proliferative status (2). 3PGDH protein is also highly expressed in adult and fetal brain tissues (3). 3PGDH protein plays an important role in the metabolism, development, and function of the central nervous system (3) and its deficiency is a treatable congential error (4-5) that impairs L-serine biosynthesis which is characterized by congenital microcephaly, psychomotor retardation, and seizures (3).
- ID gène
- 26227
- UniProt
- O43175
- Pathways
- Metabolism of Steroid Hormones and Vitamin D, L'effet Warburg
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