PMP22 anticorps (AA 101-160) (AbBy Fluor® 647)
Aperçu rapide pour PMP22 anticorps (AA 101-160) (AbBy Fluor® 647) (ABIN911562)
Antigène
Voir toutes PMP22 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 101-160
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Réactivité croisée
- Souris, Rat
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Homologie
- Human
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human PMP-22
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Isotype
- IgG
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Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Date de péremption
- 12 months
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- PMP22 (Peripheral Myelin Protein 22 (PMP22))
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Autre désignation
- PMP22
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Sujet
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Synonyms: DSS, HNPP, CMT1A, CMT1E, GAS-3, Sp110, HMSNIA, Peripheral myelin protein 22, PMP-22, Growth arrest-specific protein 3, PMP22, GAS3
Background: PMP22 is a 22 kDa glycoprotein expressed in the compact myelin of the peripheral nervous system. In the peripheral nervous system, PMP 22 is produced by myelinating Schwann cells and is coexpressed with the genes for myelin basic protein (MBP) during nerve development and regeneration. Alterations in the level of this protein cause several genetic human diseases. If the protein is duplicated, patients develop Charcot Marie Tooth disease. If one copy of the gene is deleted, they suffer from the inherited tendency to pressure palsies.
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ID gène
- 5376
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UniProt
- Q01453
Antigène
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