TMEM123 anticorps (AA 101-180) (HRP)
Aperçu rapide pour TMEM123 anticorps (AA 101-180) (HRP) (ABIN911742)
Antigène
Voir toutes TMEM123 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 101-180
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Réactivité croisée
- Humain, Souris, Rat
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Homologie
- Dog,Cow,Pig,Horse
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human Porimin
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Conseil sur la manipulation
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Date de péremption
- 12 months
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- TMEM123 (Transmembrane Protein 123 (TMEM123))
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Autre désignation
- Porimin
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Sujet
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Synonyms: KCT3, Keratinocytes associated transmembrane protein 3, Pro oncosis receptor inducing membrane injury, Serine/threonine rich receptor, TMEM123, Transmembrane protein 123, PORIM_HUMAN.
Background: This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti PORIMIN (pro oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.
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ID gène
- 114908
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Pathways
- Regulation of Cell Size
Antigène
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