RBM38 anticorps (AA 51-150) (Biotin)

N° du produit ABIN913185

Cet anticorps anti-RBM38 est un anticorps Lapin Polyclonal détectant RBM38 dans ELISA, IHC (p) et IHC (fro). Adapté pour Humain.

Aperçu rapide pour RBM38 anticorps (AA 51-150) (Biotin) (ABIN913185)

Antigène: RBM38 (RNA Binding Motif Protein 38 (RBM38))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RBM38 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-RBM38 anticorps (Biotin)

Épitope: AA 51-150

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human RBM38

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur RBM38

Antigène: RBM38 (RNA Binding Motif Protein 38 (RBM38))

Autre désignation: RBM38

Sujet:

Synonyms: SEB4D, CLL associated antigen KW 5, CLL-associated antigen KW-5, HSRNASEB, RBM38, RBM38_HUMAN, RNA binding mot protein 38, RNA binding protein 38, RNA binding region RNP1, RRM containing 1, RNA binding region containing protein 1, RNA-binding mot protein 38, RNA-binding protein 38, RNA-binding region-containing protein 1, RNPC1, SEB4, SEB4B, ssDNA binding protein SEB4, ssDNA-binding protein SEB4.

Background: RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation.

ID gène: 55544

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development