SRRM1 anticorps (AA 21-120) (HRP)

N° du produit ABIN916455

Cet anticorps anti-SRRM1 est un anticorps Lapin Polyclonal détectant SRRM1 dans WB, ELISA, IHC (p) et IHC (fro). Adapté pour Souris.

Aperçu rapide pour SRRM1 anticorps (AA 21-120) (HRP) (ABIN916455)

Antigène: SRRM1 (Serine/arginine Repetitive Matrix 1 (SRRM1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SRRM1 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-SRRM1 anticorps (HRP)

Épitope: AA 21-120

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SRRM1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur SRRM1

Antigène: SRRM1 (Serine/arginine Repetitive Matrix 1 (SRRM1))

Autre désignation: SRRM1

Sujet:

Synonyms: Ser/Arg related nuclear matrix protein, Ser/Arg-related nuclear matrix protein, Serine/arginine repetitive matrix protein 1, SR related nuclear matrix protein of 160 kDa, SR-related nuclear matrix protein of 160 kDa, SRm160, Srrm1, SRRM1_HUMAN.

Background: Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double- or single-stranded nucleic acid substrates.

ID gène: 10250