UBE2V1 anticorps (AA 51-147) (Cy7)

N° du produit ABIN919166

L’anticorps anti-UBE2V1 Polyclonal Lapin est utilisé pour la détection de UBE2V1 dans des échantillons de Humain et Rat. Il a été validé pour WB, FACS, IF (cc) et IF (p).

Aperçu rapide pour UBE2V1 anticorps (AA 51-147) (Cy7) (ABIN919166)

Antigène: UBE2V1 (Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE2V1 est conjugé à/à la Cy7

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-UBE2V1 anticorps (Cy7)

Épitope: AA 51-147

Réactivité croisée: Humain, Rat

Homologie: Mouse,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human UBE2V1

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur UBE2V1

Antigène: UBE2V1 (Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))

Autre désignation: UBE2V1

Sujet:

Synonyms: CIR1, CROC-1, CROC1, CROC1A, TRAF6-regulated IKK activator 1 beta Uev1A, UB2V1_HUMAN, UBE2V 1, UBE2V, UBE2V1, Ubiquitin conjugating enzyme E2 variant 1, Ubiquitin-conjugating enzyme E2 variant 1, UEV-1, UEV1.

Background: Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through Lys-63. This type of poly-ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF-kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.

ID gène: 7335

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades