TLR9 anticorps (Internal Region)

N° du produit ABIN920629

Cet anticorps Lapin Polyclonal détecte spécifiquement TLR9 dans WB et ICC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TLR9 anticorps (Internal Region) (ABIN920629)

Antigène: TLR9 (Toll-Like Receptor 9 (TLR9))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR9 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Détail du produit anti-TLR9 anticorps

Épitope: Internal Region

Attributs du produit: Positive Control: Jurkat cell lysate. Located in the membrane, and highly expressed in spleen, lymph node, tonsil and peripheral blood leukocytes, especially in plasmacytoid pre-dendritic cells. Levels are much lower in monocytes and CD11c+ immature dendritic cells. Also detected in lung and liver.

Purification: Antigen Immunoaffinity purified

Immunogène: Rabbit polyclonal TLR9 antibody was raised against a peptide corresponding to 15 amino acids near the center of human TLR9.

Isotype: IgG

Information d'application

Indications d'application: Western blot: use at 0.5-1 µg/mL

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline with 0.02% sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur TLR9

Antigène: TLR9 (Toll-Like Receptor 9 (TLR9))

Sujet: Toll-like receptors (TRLs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. TLR9 forms a subfamily with TLR7 and TLR8 that recognize viral RNA and CpG DNA sequences and are localized in intracellular acidic compartments such as the phagolysosome. Unlike other TLRs which act through adaptor molecules such as TOLLIP, TIRAP, TRIF, and MyD88 to activate various kinases and transcription factors to respond to potential infection, TRL9 is strictly dependent on MyD88. Synonyms:

Poids moléculaire: 116 kDa

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades