TLR3 anticorps (Biotin)

N° du produit ABIN920708

L’anticorps Souris Monoclonal anti-TLR3 a été validé pour WB et FACS. Il convient pour détecter TLR3 dans des échantillons de Humain.

Aperçu rapide pour TLR3 anticorps (Biotin) (ABIN920708)

Antigène: TLR3 (Toll-Like Receptor 3 (TLR3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TLR3 est conjugé à/à la Biotin

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-TLR3 anticorps (Biotin)

Specificité: Reacts with TLR3.

Stérilité: 0.2 μm filtered

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: (intracellular) Use at a 1:10 dilution. Western blot: Use at a 1:10 dilution.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.5 mL of 0.2 µm sterile filtered antibody solution at 100 µg/mL in PBS containing 0.1% protein stabilizer and 0.02% sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur TLR3

Antigène: TLR3 (Toll-Like Receptor 3 (TLR3))

Autre désignation: TLR3

Sujet: Toll-like receptors (TLR) are highly conserved throughout evolution and have been implicated in the innate defence to many pathogens. In Drosophila toll is required for the anti-fungal response, while the related 18-wheeler is involved in antibacterial defences. In mammals, TLR identified as type I membrane signalling receptors with pattern recognition capabilies, have been implicated in the innate host defence to pathogens. As investigated so far all functional characterized TLR signal via the TLR/IL-1 receptor (IL-1R) pathway where recruitment of MyD88 seems to be essential. Viral replication within infected cells results in generation of dsRNA which can stimulate immune cells. Recent data show that TLR3 in viral recognition and innate defence.

Pathways: Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades