CDK8 anticorps (C-Term)

N° du produit ABIN926004

Détail du produit anti-CDK8 anticorps

Antigène: CDK8 (Cyclin-Dependent Kinase 8 (CDK8))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Chien, Poulet, Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK8 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Souris, Rat (Rattus), Chien, Poisson zebré (Brachydanio rerio), Grenouille, Poulet

Immunogène: CDK8 antibody was raised in rabbit using the C terminal of CDK8 as the immunogen

Information d'application

Indications d'application: WB: 1.25 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

CDK8 Blocking Peptide, catalog no. 33R-3399, is also available for use as a blocking control in assays to test for specificity of this CDK8 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur CDK8

Antigène: CDK8 (Cyclin-Dependent Kinase 8 (CDK8))

Autre désignation: CDK8 (CDK8 Produits)

Synonymes: anticorps K35, anticorps wu:fk95h11, anticorps cyclin dependent kinase 8, anticorps cyclin-dependent kinase 8, anticorps cyclin-dependent kinase 8 S homeolog, anticorps Cyclin-dependent kinase 8, anticorps cyclin dependent kinase 19, anticorps CDK8, anticorps Cdk8, anticorps cdk8, anticorps cdk8.S, anticorps cdk-8, anticorps CDK19

Sujet: The protein encoded by CDK8 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery. Synonyms: Polyclonal CDK8 antibody, Anti-CDK8 antibody, cyclin-dependent kinase 8 antibody.

Pathways: Cycle Cellulaire, Regulation of Lipid Metabolism by PPARalpha