Topoisomerase II alpha anticorps (C-Term)

N° du produit ABIN926005

Cet anticorps Lapin Polyclonal détecte spécifiquement Topoisomerase II alpha dans WB. Il présente une réactivité envers Humain, Souris, Rat, Porc et Chien.

Aperçu rapide pour Topoisomerase II alpha anticorps (C-Term) (ABIN926005)

Antigène: Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

Reactivité: Humain, Souris, Rat, Porc, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Topoisomerase II alpha est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Topoisomerase II alpha anticorps

Épitope: C-Term

Réactivité croisée: Chien, Rat (Rattus), Souris, Porc

Immunogène: TOP2 A antibody was raised in rabbit using the C terminal of TOP2 as the immunogen

Information d'application

Indications d'application: WB: 1.25 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

TOP2A Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this TOP2A antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur Topoisomerase II alpha

Antigène: Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

Autre désignation: TOP2A

Sujet: TOP2A is a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromsome 17 and the beta gene is localized to chromosome 3. Synonyms: Polyclonal TOP2A antibody, Anti-TOP2A antibody, topoisomerase, DNA II alpha 170kDa antibody.

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases