DDB2 anticorps (C-Term)

N° du produit ABIN926426

L’anticorps Lapin Polyclonal anti-DDB2 a été validé pour WB. Il convient pour détecter DDB2 dans des échantillons de Humain.

Aperçu rapide pour DDB2 anticorps (C-Term) (ABIN926426)

Antigène: DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDB2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DDB2 anticorps

Épitope: C-Term

Purification: Purified

Immunogène: DDB2 antibody was raised in rabbit using the C terminal of DDB2 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

DDB2 Blocking Peptide, (ABIN939596), is also available for use as a blocking control in assays to test for specificity of this DDB2 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur DDB2

Antigène: DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))

Autre désignation: DDB2

Sujet: This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Synonyms: Polyclonal DDB2 antibody, Anti-DDB2 antibody, damage-specific DNA binding protein 2, 48kDa antibody, DDBB antibody, FLJ34321 antibody, UV-DDB2 antibody.

Pathways: Réparation de l'ADN