TCHP anticorps (C-Term)

N° du produit ABIN926521

Cet anticorps Lapin Polyclonal détecte spécifiquement TCHP dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour TCHP anticorps (C-Term) (ABIN926521)

Antigène: TCHP (Trichoplein, Keratin Filament Binding (TCHP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TCHP est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TCHP anticorps

Épitope: C-Term

Purification: Purified

Immunogène: TCHP antibody was raised in rabbit using the C terminal of TCHP as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

TCHP Blocking Peptide, (ABIN939497), is also available for use as a blocking control in assays to test for specificity of this TCHP antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur TCHP

Antigène: TCHP (Trichoplein, Keratin Filament Binding (TCHP))

Autre désignation: TCHP

Sujet: TCHP is a tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. It inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. It may act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. And it also may regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells. Synonyms: Polyclonal TCHP antibody, Anti-TCHP antibody, trichoplein, keratin filament binding antibody, MGC10854 antibody.