Hexokinase 1 anticorps (N-Term)

N° du produit ABIN926654

L’anticorps anti-Hexokinase 1 Polyclonal Lapin est utilisé pour la détection de Hexokinase 1 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour Hexokinase 1 anticorps (N-Term) (ABIN926654)

Antigène: Hexokinase 1 (HK1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Hexokinase 1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Hexokinase 1 anticorps

Épitope: N-Term

Purification: Purified

Immunogène: HK1 antibody was raised in rabbit using the N terminal of HK1 as the immunogen

Information d'application

Indications d'application: Optimal conditions should be determined by the investigator.

Commentaires:

HK1 Blocking Peptide, (ABIN937173), is also available for use as a blocking control in assays to test for specificity of this HK1 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur Hexokinase 1

Antigène: Hexokinase 1 (HK1)

Autre désignation: HK1

Sujet: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus, the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein. Synonyms: Polyclonal HK1 antibody, Anti-HK1 antibody, hexokinase 1 antibody, HK1-ta antibody, HK1-tb antibody, HK1-tc antibody, HKI antibody, HXK1 antibody.

Pathways: Carbohydrate Homeostasis, L'effet Warburg