Factor XI anticorps (C-Term)

N° du produit ABIN926655

Détail du produit anti-Factor XI anticorps

Antigène: Factor XI (F11) (Coagulation Factor XI (F11))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Factor XI est non-conjugé

Application: Western Blotting (WB)

Purification: Purified

Immunogène: F11 antibody was raised in rabbit using the C terminal of F11 as the immunogen

Information d'application

Indications d'application: Optimal conditions should be determined by the investigator.

Commentaires:

F11 Blocking Peptide, catalog no. 33R-7950, is also available for use as a blocking control in assays to test for specificity of this F11 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur Factor XI

Antigène: Factor XI (F11) (Coagulation Factor XI (F11))

Autre désignation: F11 (F11 Produits)

Synonymes: anticorps FXI, anticorps 1600027G01Rik, anticorps AI503996, anticorps Cf11, anticorps LRRGT00086, anticorps coagulation factor XI, anticorps F11, anticorps CpipJ_CPIJ000593, anticorps CpipJ_CPIJ001060, anticorps CpipJ_CPIJ002752, anticorps CpipJ_CPIJ003631, anticorps CpipJ_CPIJ004041, anticorps CpipJ_CPIJ004093

Sujet: This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. Synonyms: Polyclonal F11 antibody, Anti-F11 antibody, coagulation factor XI antibody, FXI antibody, MGC141891 antibody.